Dr Wolf is a clinical haematologist and his current appointment is as consultant haematologist in the Division of Cancer Medicine at the Peter MacCallum Cancer Centre. His main research and clinical interests are in the treatment of patients with haematological malignancies such as lymphoma, myeloma and leukaemia. He is past chairman of the Australasian Leukaemia and Lymphoma Group, the main co-operative group conducting clinical trials in haematological cancers.

Dr Wolf  also consults on a full range of haematological problems such as anaemia, iron metabolism, thrombosis and bleeding disorders.

Dr Wolf has admitting rights to a number of private hospitals including Masada, Cabrini and Epworth.