Professor O’Sullivan is a cardiologist with a clinical focus in heart failure, particularly “stiff” heart failure (Heart Failure with Preserved Ejection Fraction / HFpEF), which is now the most common form of heart failure globally. He is Level III SCMR certified in cardiac MRI, which he uses to improve diagnosis and management of this condition. He also has an interest in management of the underlying conditions that drive this type of heart failure - such as diabetes, high blood pressure, and obesity - management of which are critical to improve outcome. Professor O’Sullivan’s leads a research program in this condition at the Royal Prince Alfred Hospital, the Heart Research Institute, and the University of Sydney which is at the forefront of new diagnostic and treatments.

Professor O’Sullivan graduated from the National University of Ireland, Galway and undertook training in Internal Medicine at University College Hospital Galway, University College Cork, and the National Cardiac Centre at the Mater Misericordiae Hospital, Dublin. He was awarded FRCPI in 2006. He received his Certificate of Satisfactory Completion of Specialist Training from the Royal College of Physicians of Ireland, with rotations in cardiac transplantation, interventional cardiology, cardiac electrophysiology, and heart failure.

Professor O’Sullivan then undertook the US medical licensing examinations, receiving ECFMG certification in 2011. He then undertook training at Massachusetts General Hospital (2012-2016), the main teaching hospital of Harvard Medical School, and at the Broad Institute of Harvard and MIT. Here, he undertook a postdoctoral research program in metabolic disease and functional genomics, receiving several awards including from MGH, Harvard Medical School, and the American Heart Association.

Upon relocating to Australia, A/Prof O’Sullivan undertook further training in cardiac imaging at Royal Prince Alfred Hospital. He was appointed as Clinical-Academic Cardiologist at Royal Prince Alfred Hospital and the University of Sydney in 2018, and was awarded a Chapman Fellowship (2017-2020) from Sydney Medical School. He was appointed as Adjunct Professor in the Faculty of Medicine at TU Dresden, Germany, one of the top 10 medical schools in Germany, in 2017. He is also a group leader at the Heart Research Institute. He runs a HFpEF clinic with Dr Sean Lal at RPAH, and his clinical research is supported by a National Heart Foundation Future Leadership Fellowship and grants from the NSW Office of Health and Medical Research. A/Prof O’Sullivan has published novel findings in HFpEF in Nature Communications, Eur J Heart Failure, and elsewhere, and is frequently asked to give lectures on this topic by national and international cardiac societies.

Interests

• Heart Failure
• Heart Failure with preserved Ejection Fraction
• Diabetic Cardiomyopathy
• Cardiac MRI

Hospitals

Private - Strathfield Private Hospital
Public - Royal Prince Alfred Hospital